Pezzuto points out that these studies add a whole new dimension to the old adage “you are what you eat.” He has authored more than 600 scientific studies and says his work on grapes shows actual changes in gene expression. “It’s really amazing.”
The study found that adding grapes to a high-fat diet also boosted levels of antioxidant genes and delayed natural death. However, Pezzuto acknowledges that translating mouse lifespan years into human lifespans is not an exact science. His best estimate, however, is that the changes observed in the study would correspond to an extra 4-5 years of lifespan in humans.
Another study by Dr. Pezzuto and his team was published in the journal Antioxidants. It reported that eating grapes changed gene expression in the brain and had a positive effect on behavior and cognitive abilities impaired by a high-fat diet. The third study, published in the journal Food & Function by a team led by Dr. Jeffrey Idle, showed that in addition to changes in gene expression, grapes are believed to alter metabolism.
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