This blood type was first discovered in Mumbai, India in 1952, and is extremely rare in China.The proportion of people with this blood type in the country is only 1 in 100,000.There are only hundreds of cases in the country.
Not long ago, a pregnant mother visited a hospital in Changsha. During the diagnosis and treatment, the doctor found that the pregnant woman’s ABO blood type,Positive and negative stereotypes do not match, positive stereotypes show O-type characteristics, reverse stereotypes show B-type characteristics, anti-screening positive and self-negative.
The abnormal result aroused the vigilance of the doctor, so after the use of anti-H, saline anti-screening method, absorption and dispersion test micro-column gel method, test tube method and other related blood type serological experiments, it was initially considered to be Bombay-like blood type.
It is understood that in order to ensure the accuracy, the doctor carried out a blood type gene test for him. According to the results,The serology is Mumbai-like type B, and the FUT-1 gene sequencing results are in line with FUT1*01W.37 (weak expression of H antigen) published by ISBT International Society for Blood Transfusion.The sequencing result is shown as FUT1*01W.37//FUT1*01W.37.
The ABO gene sequencing results were in line with B101/O02 published by ISBT International Society for Blood Transfusion. The patient’s gene expresses normal B-glycosyltransferase activity, excluding ABO-glycosyltransferase gene variants leading to ABO subtypes.
